Determination of Dapoxetine Hydrochloride in Human Plasma by HPLC–MS/MS and Its Application in a Bioequivalence Study

Dapoxetine is used for the treatment of premature ejaculation. The present study developed an HPLC–MS/MS method to determine the levels of dapoxetine in human plasma processed using simple protein precipitation. Dapoxetine-d(7) was selected as the internal standard. The established method was perfor...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Gao, Zhanwang, Qin, Fei, Chen, Kehan, Wang, Jiansong, Wang, Lingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101379/
https://www.ncbi.nlm.nih.gov/pubmed/35566058
http://dx.doi.org/10.3390/molecules27092707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101379/
https://www.ncbi.nlm.nih.gov/pubmed/35566058
http://dx.doi.org/10.3390/molecules27092707

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