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Determination of Dapoxetine Hydrochloride in Human Plasma by HPLC–MS/MS and Its Application in a Bioequivalence Study
Dapoxetine is used for the treatment of premature ejaculation. The present study developed an HPLC–MS/MS method to determine the levels of dapoxetine in human plasma processed using simple protein precipitation. Dapoxetine-d(7) was selected as the internal standard. The established method was perfor...
Autores principales: | Zhang, Xin, Gao, Zhanwang, Qin, Fei, Chen, Kehan, Wang, Jiansong, Wang, Lingli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101379/ https://www.ncbi.nlm.nih.gov/pubmed/35566058 http://dx.doi.org/10.3390/molecules27092707 |
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