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Copy Number Alterations as Novel Biomarkers and Therapeutic Targets in Colorectal Cancer

SIMPLE SUMMARY: Copy number alterations (CNAs) occur due to changes to DNA structure that lead to the gain/amplification or loss/deletion of copies of DNA sections from a normal genome. These CNAs have been shown to impact gene expression and appear to play a significant role in the pathogenesis of...

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Detalles Bibliográficos
Autores principales: Tan, Elaine S., Knepper, Todd C., Wang, Xuefeng, Permuth, Jennifer B., Wang, Liang, Fleming, Jason B., Xie, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101426/
https://www.ncbi.nlm.nih.gov/pubmed/35565354
http://dx.doi.org/10.3390/cancers14092223