Cargando…

Copy Number Alterations as Novel Biomarkers and Therapeutic Targets in Colorectal Cancer

SIMPLE SUMMARY: Copy number alterations (CNAs) occur due to changes to DNA structure that lead to the gain/amplification or loss/deletion of copies of DNA sections from a normal genome. These CNAs have been shown to impact gene expression and appear to play a significant role in the pathogenesis of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tan, Elaine S., Knepper, Todd C., Wang, Xuefeng, Permuth, Jennifer B., Wang, Liang, Fleming, Jason B., Xie, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101426/ https://www.ncbi.nlm.nih.gov/pubmed/35565354 http://dx.doi.org/10.3390/cancers14092223

Ejemplares similares

Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer
por: Palshof, Jesper Andreas, et al.
Publicado: (2017)

Association of Age With Treatment-Related Adverse Events and Survival in Patients With Metastatic Colorectal Cancer
por: Meng, Lingbin, et al.
Publicado: (2023)

NDRG2 gene copy number is not altered in colorectal carcinoma
por: Lorentzen, Anders, et al.
Publicado: (2017)

Genomic copy number alterations as biomarkers for triple negative pregnancy-associated breast cancer
por: Suelmann, B. B. M., et al.
Publicado: (2022)

Copy Number Alterations and Methylation in Ewing's Sarcoma
por: Jahromi, Mona S., et al.
Publicado: (2011)

Copy-number-variation and copy-number-alteration region detection by cumulative plots
por: Li, Wentian, et al.
Publicado: (2009)

Copy number variation and genomic alterations in health and disease
por: Patrinos, George P, et al.
Publicado: (2009)

Functional Copy-Number Alterations in Cancer
por: Taylor, Barry S., et al.
Publicado: (2008)

Signatures of copy number alterations in human cancer
por: Steele, Christopher D., et al.
Publicado: (2022)

Prognostic Value of Copy Number Alteration Burden in Early-Stage Breast Cancer and the Construction of an 11-Gene Copy Number Alteration Model
por: Wang, Dingyuan, et al.
Publicado: (2022)

Using Copy Number Alterations to Identify New Therapeutic Targets for Bladder Carcinoma
por: Conconi, Donatella, et al.
Publicado: (2016)

The repertoire of copy number alteration signatures in human cancer
por: Tao, Ziyu, et al.
Publicado: (2023)

Copy number alteration of neuropeptides and receptors in multiple cancers
por: Zhao, Min, et al.
Publicado: (2017)

Copy number and transcriptome alterations associated with metastatic lesion response to treatment in colorectal cancer
por: Gambaro, Karen, et al.
Publicado: (2021)

Exploratory Analysis of the Copy Number Alterations in Glioblastoma Multiforme
por: Freire, Pablo, et al.
Publicado: (2008)

Coping with cancer genes altered by copy number
por: Wolf, Natalie K., et al.
Publicado: (2015)

Pan-cancer patterns of somatic copy-number alteration
por: Zack, Travis I., et al.
Publicado: (2013)

BRAF Mutations Are Associated with Poor Survival Outcomes in Advanced-stage Mismatch Repair-deficient/Microsatellite High Colorectal Cancer
por: Tan, Elaine, et al.
Publicado: (2022)

Mutation and Copy Number Alterations Analysis of KIF23 in Glioma
por: Zhao, Zheng, et al.
Publicado: (2021)

Prognostic impact and the relevance of PTEN copy number alterations in patients with advanced colorectal cancer (CRC) receiving bevacizumab*
por: Price, Timothy J, et al.
Publicado: (2013)

Early Breast Cancer Evolution by Autosomal Broad Copy Number Alterations
por: Larsen, Joseph R., et al.
Publicado: (2022)

Comprehensive molecular analysis based on somatic copy number alterations in intramucosal colorectal neoplasias and early invasive colorectal cancers
por: Sugai, Tamotsu, et al.
Publicado: (2018)

The landscape of somatic copy-number alteration across human cancers
por: Beroukhim, Rameen, et al.
Publicado: (2010)

A Comprehensive Characterization of Genome-Wide Copy Number Aberrations in Colorectal Cancer Reveals Novel Oncogenes and Patterns of Alterations
por: Xie, Tao, et al.
Publicado: (2012)

Systematic identification of mutations and copy number alterations associated with cancer patient prognosis
por: Smith, Joan C, et al.
Publicado: (2018)

Recurrent Chromosomal Copy Number Alterations in Sporadic Chordomas
por: Le, Long Phi, et al.
Publicado: (2011)

Determining Frequent Patterns of Copy Number Alterations in Cancer
por: Rapaport, Franck, et al.
Publicado: (2010)

Histotype-specific copy-number alterations in ovarian cancer
por: Huang, Ruby YunJu, et al.
Publicado: (2012)

Patterns of chromosomal copy-number alterations in intrahepatic cholangiocarcinoma
por: Dalmasso, Cyril, et al.
Publicado: (2015)

Deciphering the chronology of copy number alterations in Multiple Myeloma
por: Aktas Samur, Anil, et al.
Publicado: (2019)

Subcortical brain alterations in carriers of genomic copy number variants
por: Kumar, Kuldeep, et al.
Publicado: (2023)

The mitochondrial DNA 4,977-bp deletion and its implication in copy number alteration in colorectal cancer
por: Chen, Tao, et al.
Publicado: (2011)

Molecular profiling and genome‐wide analysis based on somatic copy number alterations in advanced colorectal cancers
por: Sugai, Tamotsu, et al.
Publicado: (2017)

Copy Number Alterations of Depressed Colorectal Neoplasm Predict the Survival and Response to Oxaliplatin in Proximal Colon Cancer
por: Chang, Li-Chun, et al.
Publicado: (2020)

Comparative Analysis of Methods for Identifying Recurrent Copy Number Alterations in Cancer
por: Yuan, Xiguo, et al.
Publicado: (2012)

Uncoupling of gene expression from copy number presents therapeutic opportunities in aneuploid cancers
por: Mohanty, Vakul, et al.
Publicado: (2021)

Identification of genomic functional hotspots with copy number alteration in liver cancer
por: Hsiao, Tzu-Hung, et al.
Publicado: (2013)

Identification of Breast Cancer Subtype-Specific Biomarkers by Integrating Copy Number Alterations and Gene Expression Profiles
por: Cava, Claudia, et al.
Publicado: (2021)

Genome-Wide Scan for Copy Number Alteration Association with Relapse-Free Survival in Colorectal Cancer with Liver Metastasis Patients
por: Yang, Po-Sheng, et al.
Publicado: (2018)

Copy Number Variation in Hereditary Non-Polyposis Colorectal Cancer
por: Masson, Amy L., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_t4g763ovmd7vjrc60qsf5hv9cs