Preclinical In Vitro Model to Assess the Changes in Permeability and Cytotoxicity of Polarized Intestinal Epithelial Cells during Exposure Mimicking Oral or Intravenous Routes: An Example of Arsenite Exposure

The gastrointestinal tract (GIT) is exposed to xenobiotics, including drugs, through both: local (oral) and systemic routes. Despite the advances in drug discovery and in vitro pre-clinical models, there is a lack of appropriate translational models to distinguish the impact of these routes of expos...

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Detalles Bibliográficos
Autores principales: Parajuli, Pravin, Gokulan, Kuppan, Khare, Sangeeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101442/
https://www.ncbi.nlm.nih.gov/pubmed/35563241
http://dx.doi.org/10.3390/ijms23094851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101442/
https://www.ncbi.nlm.nih.gov/pubmed/35563241
http://dx.doi.org/10.3390/ijms23094851

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