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Distinct AMPK-Mediated FAS/HSL Pathway Is Implicated in the Alleviating Effect of Nuciferine on Obesity and Hepatic Steatosis in HFD-Fed Mice

Nuciferine (Nuci), the main aporphine alkaloid component in lotus leaf, was reported to reduce lipid accumulation in vitro. Herein we investigated whether Nuci prevents obesity in high fat diet (HFD)-fed mice and the underlying mechanism in liver/HepG2 hepatocytes and epididymal white adipose tissue...

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Detalles Bibliográficos
Autores principales: Xu, Hanyuan, Lyu, Xiaorui, Guo, Xiaonan, Yang, Hongbo, Duan, Lian, Zhu, Huijuan, Pan, Hui, Gong, Fengying, Wang, Linjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101490/
https://www.ncbi.nlm.nih.gov/pubmed/35565866
http://dx.doi.org/10.3390/nu14091898