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An Ex Vivo 3D Tumor Microenvironment-Mimicry Culture to Study TAM Modulation of Cancer Immunotherapy

Tumor-associated macrophages (TAMs) accumulate in the solid tumor microenvironment (TME) and have been shown to promote tumor growth and dampen antitumor immune responses. TAM-mediated suppression of T-cell antitumor reactivity is considered to be a major obstacle for many immunotherapies, including...

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Detalles Bibliográficos
Autores principales: Li, Yan-Ruide, Yu, Yanqi, Kramer, Adam, Hon, Ryan, Wilson, Matthew, Brown, James, Yang, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101510/
https://www.ncbi.nlm.nih.gov/pubmed/35563889
http://dx.doi.org/10.3390/cells11091583