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Downregulation of miR-122-5p Activates Glycolysis via PKM2 in Kupffer Cells of Rat and Mouse Models of Non-Alcoholic Steatohepatitis

Non-alcoholic steatohepatitis (NASH) has pathological characteristics similar to those of alcoholic hepatitis, despite the absence of a drinking history. The greatest threat associated with NASH is its progression to cirrhosis and hepatocellular carcinoma. The pathophysiology of NASH is not fully un...

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Detalles Bibliográficos
Autores principales: Inomata, Yosuke, Oh, Jae-Won, Taniguchi, Kohei, Sugito, Nobuhiko, Kawaguchi, Nao, Hirokawa, Fumitoshi, Lee, Sang-Woong, Akao, Yukihiro, Takai, Shinji, Kim, Kwang-Pyo, Uchiyama, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101520/
https://www.ncbi.nlm.nih.gov/pubmed/35563621
http://dx.doi.org/10.3390/ijms23095230