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Sirt1 overexpression attenuates Western‐style diet‐induced aortic stiffening in mice
Increased arterial stiffness is a cardiovascular disease risk factor in the setting of advancing age and Western diet (WD) induced obesity. Increases in large artery stiffness, as measured by pulse wave velocity (PWV), occur within 8 weeks of WD feeding in mice. Sirtuin‐1 (Sirt1), a NAD‐dependent de...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101596/ https://www.ncbi.nlm.nih.gov/pubmed/35561022 http://dx.doi.org/10.14814/phy2.15284 |