Sirt1 overexpression attenuates Western‐style diet‐induced aortic stiffening in mice

Increased arterial stiffness is a cardiovascular disease risk factor in the setting of advancing age and Western diet (WD) induced obesity. Increases in large artery stiffness, as measured by pulse wave velocity (PWV), occur within 8 weeks of WD feeding in mice. Sirtuin‐1 (Sirt1), a NAD‐dependent de...

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Detalles Bibliográficos
Autores principales: Gogulamudi, Venkateswara R., Machin, Daniel R., Henson, Grant D., Lim, Jisok, Bramwell, Richard C., Durrant, Jessica R., Donato, Anthony J., Lesniewski, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101596/
https://www.ncbi.nlm.nih.gov/pubmed/35561022
http://dx.doi.org/10.14814/phy2.15284

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