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A Short ERAP2 That Binds IRAP Is Expressed in Macrophages Independently of Gene Variation

The M1 zinc metalloproteases ERAP1, ERAP2, and IRAP play a role in HLA-I antigen presentation by refining the peptidome either in the ER (ERAP1 and ERAP2) or in the endosomes (IRAP). They have also been entrusted with other, although less defined, functions such as the regulation of the angiotensin...

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Detalles Bibliográficos
Autores principales: Mattorre, Benedetta, Caristi, Silvana, Donato, Simona, Volpe, Emilia, Faiella, Marika, Paiardini, Alessandro, Sorrentino, Rosa, Paladini, Fabiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101739/
https://www.ncbi.nlm.nih.gov/pubmed/35563348
http://dx.doi.org/10.3390/ijms23094961