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Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells

1,8-naphthyridine-3-carboxamide structures were previously identified as a promising scaffold from which to obtain CB2R agonists with anticancer and anti-inflammatory activity. This work describes the synthesis and functional characterization of new 1,8-naphthyridin-2(1H)-one-3-carboxamides with hig...

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Detalles Bibliográficos
Autores principales: Gado, Francesca, Ferrisi, Rebecca, Di Somma, Sarah, Napolitano, Fabiana, Mohamed, Kawthar A., Stevenson, Lesley A., Rapposelli, Simona, Saccomanni, Giuseppe, Portella, Giuseppe, Pertwee, Roger G., Laprairie, Robert B., Malfitano, Anna Maria, Manera, Clementina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101764/
https://www.ncbi.nlm.nih.gov/pubmed/35566369
http://dx.doi.org/10.3390/molecules27093019