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Solubility and Permeability Enhancement of Oleanolic Acid by Solid Dispersion in Poloxamers and γ-CD

Oleanolic acid (OA) is a pentacyclic triterpenoid widely found in the Oleaceae family, and it represents 3.5% of the dry weight of olive leaves. OA has many pharmacological activities, such as hepatoprotection, anti-inflammatory, anti-oxidant, anti-diabetic, anti-tumor, and anti-microbic activities....

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Detalles Bibliográficos
Autores principales: De Stefani, Chiara, Lodovichi, Jessika, Albonetti, Laura, Salvatici, Maria Cristina, Quintela, José Carlos, Bilia, Anna Rita, Bergonzi, Maria Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101807/
https://www.ncbi.nlm.nih.gov/pubmed/35566392
http://dx.doi.org/10.3390/molecules27093042