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Enantioselective Organocatalyzed Michael Addition of Isobutyraldehyde to Maleimides in Aqueous Media

Thiourea was introduced into (R,R)-1,2-diphenylethylenediamine as an organocatalyst to promote the reaction between isobutyraldehydes and maleimides. Enantioselective Michael addition reaction was carried out as an eco-friendly method using water as the solvent. As a result of the reaction between i...

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Detalles Bibliográficos
Autores principales: Shim, Jae Ho, Cheun, Seok Hyun, Kim, Hyeon Soo, Ha, Deok-Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101813/
https://www.ncbi.nlm.nih.gov/pubmed/35566109
http://dx.doi.org/10.3390/molecules27092759