Extracellular Matrix Biomimetic Hydrogels, Encapsulated with Stromal Cell-Derived Factor 1, Improve the Composition of Foetal Tissue Grafts in a Rodent Model of Parkinson’s Disease

Clinical studies have provided evidence for dopamine (DA) cell replacement therapy in Parkinson’s Disease. However, grafts derived from foetal tissue or pluripotent stem cells (PSCs) remain heterogeneous, with a high proportion of non-dopaminergic cells, and display subthreshold reinnervation of tar...

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Detalles Bibliográficos
Autores principales: Penna, Vanessa, Moriarty, Niamh, Wang, Yi, Law, Kevin C. L., Gantner, Carlos W., Williams, Richard J., Nisbet, David R., Parish, Clare L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101815/
https://www.ncbi.nlm.nih.gov/pubmed/35563037
http://dx.doi.org/10.3390/ijms23094646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101815/
https://www.ncbi.nlm.nih.gov/pubmed/35563037
http://dx.doi.org/10.3390/ijms23094646

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