Novel Small Molecule Inhibitors Targeting the IL-6/STAT3 Pathway or IL-1β

Development of small molecules that inhibit inflammatory cytokines is a desirable strategy for the treatment of inflammatory diseases such as rheumatoid arthritis (RA). Following up a previous study, we synthesized 10 novel compounds with a 2,5-diaminobenzoxazole moiety and evaluated their biologica...

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Detalles Bibliográficos
Autores principales: Yoo, Jihye, Kim, Darong, Park, Jiyoung, Kim, Young-Kook, Park Choo, Hea-Young, Woo, Hyun Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101866/
https://www.ncbi.nlm.nih.gov/pubmed/35566047
http://dx.doi.org/10.3390/molecules27092696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101866/
https://www.ncbi.nlm.nih.gov/pubmed/35566047
http://dx.doi.org/10.3390/molecules27092696

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