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Development, In-Vitro Characterization and Preclinical Evaluation of Esomeprazole-Encapsulated Proniosomal Formulation for the Enhancement of Anti-Ulcer Activity

Objective: The present study aimed to develop and optimize esomeprazole loaded proniosomes (EZL-PNs) to improve bioavailability and therapeutic efficacy. Method: EZL-PNs formulation was developed by slurry method and optimized by 33 box-Bhekhen statistical design software. Span 60 (surfactant), chol...

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Detalles Bibliográficos
Autores principales: Mohanty, Dibyalochan, Zafar, Ameeduzzafar, Jafar, Mohammed, Upadhyay, Atul Kumar, Haque, Mohammad Akiful, Gupta, Jeetendra Kumar, Bakshi, Vasudha, Ghoneim, Mohammed M., Alshehri, Sultan, Jahangir, Mohammed Asadullah, Ansari, Mohammed Javed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101870/
https://www.ncbi.nlm.nih.gov/pubmed/35566099
http://dx.doi.org/10.3390/molecules27092748