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Development, In-Vitro Characterization and Preclinical Evaluation of Esomeprazole-Encapsulated Proniosomal Formulation for the Enhancement of Anti-Ulcer Activity
Objective: The present study aimed to develop and optimize esomeprazole loaded proniosomes (EZL-PNs) to improve bioavailability and therapeutic efficacy. Method: EZL-PNs formulation was developed by slurry method and optimized by 33 box-Bhekhen statistical design software. Span 60 (surfactant), chol...
Autores principales: | Mohanty, Dibyalochan, Zafar, Ameeduzzafar, Jafar, Mohammed, Upadhyay, Atul Kumar, Haque, Mohammad Akiful, Gupta, Jeetendra Kumar, Bakshi, Vasudha, Ghoneim, Mohammed M., Alshehri, Sultan, Jahangir, Mohammed Asadullah, Ansari, Mohammed Javed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101870/ https://www.ncbi.nlm.nih.gov/pubmed/35566099 http://dx.doi.org/10.3390/molecules27092748 |
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