Activation of Sigma-1 Receptor Alleviates ER-Associated Cell Death and Microglia Activation in Traumatically Injured Mice

Background: Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) is associated with neuroinflammation and subsequent cell death following traumatic brain injury (TBI). The sigma-1 receptor (Sig-1R) acts as a dynamic pluripotent modulator of fundamental cellular processes at the mito...

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Detalles Bibliográficos
Autores principales: Shi, Mingming, Liu, Liang, Min, Xiaobin, Mi, Liang, Chai, Yan, Chen, Fanglian, Wang, Jianhao, Yue, Shuyuan, Zhang, Jianning, Deng, Quanjun, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102000/
https://www.ncbi.nlm.nih.gov/pubmed/35566476
http://dx.doi.org/10.3390/jcm11092348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102000/
https://www.ncbi.nlm.nih.gov/pubmed/35566476
http://dx.doi.org/10.3390/jcm11092348

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