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Microsatellite Status Detection in Gastrointestinal Cancers: PCR/NGS Is Mandatory in Negative/Patchy MMR Immunohistochemistry

SIMPLE SUMMARY: Microsatellite instability (MSI) detection has a high impact on eligibility for immune checkpoint inhibitors in gastrointestinal cancers. The appropriate detection of MSI represents the major critical issue in clinical practice, thus a better understanding of the limits related to MS...

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Detalles Bibliográficos
Autores principales: Zito Marino, Federica, Amato, Martina, Ronchi, Andrea, Panarese, Iacopo, Ferraraccio, Franca, De Vita, Ferdinando, Tirino, Giuseppe, Martinelli, Erika, Troiani, Teresa, Facchini, Gaetano, Pirozzi, Felice, Perrotta, Michele, Incoronato, Pasquale, Addeo, Raffaele, Selvaggi, Francesco, Lucido, Francesco Saverio, Caraglia, Michele, Savarese, Giovanni, Sirica, Roberto, Casillo, Marika, Lieto, Eva, Auricchio, Annamaria, Cardella, Francesca, Docimo, Ludovico, Galizia, Gennaro, Franco, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102010/
https://www.ncbi.nlm.nih.gov/pubmed/35565332
http://dx.doi.org/10.3390/cancers14092204