Functional and Structural Insights into Human PPARα/δ/γ Subtype Selectivity of Bezafibrate, Fenofibric Acid, and Pemafibrate

Among the agonists against three peroxisome proliferator-activated receptor (PPAR) subtypes, those against PPARα (fibrates) and PPARγ (glitazones) are currently used to treat dyslipidemia and type 2 diabetes, respectively, whereas PPARδ agonists are expected to be the next-generation metabolic disea...

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Detalles Bibliográficos
Autores principales: Honda, Akihiro, Kamata, Shotaro, Akahane, Makoto, Machida, Yui, Uchii, Kie, Shiiyama, Yui, Habu, Yuki, Miyawaki, Saeka, Kaneko, Chihiro, Oyama, Takuji, Ishii, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102038/
https://www.ncbi.nlm.nih.gov/pubmed/35563117
http://dx.doi.org/10.3390/ijms23094726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102038/
https://www.ncbi.nlm.nih.gov/pubmed/35563117
http://dx.doi.org/10.3390/ijms23094726

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