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In Silico and In Vitro Antimalarial Screening and Validation Targeting Plasmodium falciparum Plasmepsin V

Malaria chemotherapy is greatly threatened by the recent emergence and spread of resistance in the Plasmodium falciparum parasite against artemisinins and their partner drugs. Therefore, it is an urgent priority to develop new antimalarials. Plasmepsin V (PMV) is regarded as a superior drug target f...

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Detalles Bibliográficos
Autores principales: Ji, Xin, Wang, Zhensheng, Chen, Qianqian, Li, Jingzhong, Wang, Heng, Wang, Zenglei, Yang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102085/
https://www.ncbi.nlm.nih.gov/pubmed/35566023
http://dx.doi.org/10.3390/molecules27092670