Structure-Based Virtual Screening towards the Discovery of Novel ULK1 Inhibitors with Anti-HCC Activities

There is an urgent need to develop new effective therapies for HCC. Our previous study identified ULK1 as the potential target for HCC therapy and screened the compound XST-14 as a specific inhibitor of ULK1 to suppress HCC progression. However, the poor manufacturability of XST-14 impeded the proce...

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Detalles Bibliográficos
Autores principales: Gao, Yang, Zhou, Ziying, Zhang, Tingting, Xue, Situ, Li, Ke, Jiang, Jiandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102329/
https://www.ncbi.nlm.nih.gov/pubmed/35565977
http://dx.doi.org/10.3390/molecules27092627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102329/
https://www.ncbi.nlm.nih.gov/pubmed/35565977
http://dx.doi.org/10.3390/molecules27092627

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