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ASC proneural factors are necessary for chromatin remodeling during neuroectodermal to neuroblast fate transition to ensure the timely initiation of the neural stem cell program

BACKGROUND: In both Drosophila and mammals, the achaete-scute (ASC/ASCL) proneural bHLH transcription factors are expressed in the developing central and peripheral nervous systems, where they function during specification and maintenance of the neural stem cells in opposition to Notch signaling. In...

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Detalles Bibliográficos
Autores principales: Theodorou, Vasiliki, Stefanaki, Aikaterini, Drakos, Minas, Triantafyllou, Dafne, Delidakis, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102361/
https://www.ncbi.nlm.nih.gov/pubmed/35549704
http://dx.doi.org/10.1186/s12915-022-01300-8