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MarvelD3 Is Upregulated in Ulcerative Colitis and Has Attenuating Effects during Colitis Indirectly Stabilizing the Intestinal Barrier

In inflammatory bowel disease (IBD), the impaired intestinal barrier is mainly characterized by changes in tight junction protein expression. The functional role of the tight junction-associated MARVEL protein MARVELD3 (MD3) in IBD is yet unknown. (i) In colon biopsies from IBD patients we analyzed...

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Detalles Bibliográficos
Autores principales: Weiß, Franziska, Czichos, Carolina, Knobe, Lukas, Voges, Lena, Bojarski, Christian, Michel, Geert, Fromm, Michael, Krug, Susanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102383/
https://www.ncbi.nlm.nih.gov/pubmed/35563847
http://dx.doi.org/10.3390/cells11091541