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Data-Driven Mathematical Model of Apoptosis Regulation in Memory Plasma Cells

Memory plasma cells constitutively produce copious amounts of antibodies, imposing a critical risk factor for autoimmune disease. We previously found that plasma cell survival requires secreted factors such as APRIL and direct contact to stromal cells, which act in concert to activate NF-κB- and PI3...

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Detalles Bibliográficos
Autores principales: Burt, Philipp, Cornelis, Rebecca, Geißler, Gustav, Hahne, Stefanie, Radbruch, Andreas, Chang, Hyun-Dong, Thurley, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102437/
https://www.ncbi.nlm.nih.gov/pubmed/35563853
http://dx.doi.org/10.3390/cells11091547