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Data-Driven Mathematical Model of Apoptosis Regulation in Memory Plasma Cells
Memory plasma cells constitutively produce copious amounts of antibodies, imposing a critical risk factor for autoimmune disease. We previously found that plasma cell survival requires secreted factors such as APRIL and direct contact to stromal cells, which act in concert to activate NF-κB- and PI3...
Autores principales: | Burt, Philipp, Cornelis, Rebecca, Geißler, Gustav, Hahne, Stefanie, Radbruch, Andreas, Chang, Hyun-Dong, Thurley, Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102437/ https://www.ncbi.nlm.nih.gov/pubmed/35563853 http://dx.doi.org/10.3390/cells11091547 |
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