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Isatis tinctoria L. Leaf Extract Inhibits Replicative Senescence in Dermal Fibroblasts by Regulating mTOR-NF-κB-SASP Signaling

Senescent fibroblasts progressively deteriorate the functional properties of skin tissue. Senescent cells secrete senescence-associated secretory phenotype (SASP) factor, which causes the aging of surrounding non-senescent cells and accelerates aging in the individuals. Recent findings suggested the...

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Detalles Bibliográficos
Autores principales: Woo, Jieun, Shin, Seoungwoo, Ji, Hyanggi, Ryu, Dehun, Cho, Eunae, Kim, Youngseok, Kim, Junoh, Park, Deokhoon, Jung, Eunsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102489/
https://www.ncbi.nlm.nih.gov/pubmed/35565945
http://dx.doi.org/10.3390/nu14091979