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Isatis tinctoria L. Leaf Extract Inhibits Replicative Senescence in Dermal Fibroblasts by Regulating mTOR-NF-κB-SASP Signaling
Senescent fibroblasts progressively deteriorate the functional properties of skin tissue. Senescent cells secrete senescence-associated secretory phenotype (SASP) factor, which causes the aging of surrounding non-senescent cells and accelerates aging in the individuals. Recent findings suggested the...
Autores principales: | Woo, Jieun, Shin, Seoungwoo, Ji, Hyanggi, Ryu, Dehun, Cho, Eunae, Kim, Youngseok, Kim, Junoh, Park, Deokhoon, Jung, Eunsun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102489/ https://www.ncbi.nlm.nih.gov/pubmed/35565945 http://dx.doi.org/10.3390/nu14091979 |
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