Cargando…

Identification of potential pathogenic genes for severe aplastic anemia by whole‐exome sequencing

BACKGROUND: Severe aplastic anemia (SAA) is a syndrome of severe bone marrow failure due to hyperfunction of CD8+ T cells. While, the genetic background of SAA is still unknown. In this study, we tried to explore the possible genetic variants in CD8+ T cells of SAA patients. METHODS: We performed wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yang, Zhang, Yu, Ge, Hongyu, Li, Nianbin, Liu, Chunyan, Wang, Ting, Fu, Rong, Shao, Zonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102512/
https://www.ncbi.nlm.nih.gov/pubmed/35435273
http://dx.doi.org/10.1002/jcla.24438