MicroRNA-145 Impairs Classical Non-Homologous End-Joining in Response to Ionizing Radiation-Induced DNA Double-Strand Breaks via Targeting DNA-PKcs

DNA double-strand breaks (DSBs) are one of the most lethal types of DNA damage due to the fact that unrepaired or mis-repaired DSBs lead to genomic instability or chromosomal aberrations, thereby causing cell death or tumorigenesis. The classical non-homologous end-joining pathway (c-NHEJ) is the ma...

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Detalles Bibliográficos
Autores principales: Sudhanva, Muddenahalli Srinivasa, Hariharasudhan, Gurusamy, Jun, Semo, Seo, Gwanwoo, Kamalakannan, Radhakrishnan, Kim, Hyun Hee, Lee, Jung-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102532/
https://www.ncbi.nlm.nih.gov/pubmed/35563814
http://dx.doi.org/10.3390/cells11091509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102532/
https://www.ncbi.nlm.nih.gov/pubmed/35563814
http://dx.doi.org/10.3390/cells11091509

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