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Inhibition of USP14 suppresses ferroptosis and inflammation in LPS-induced goat mammary epithelial cells through ubiquitylating the IL-6 protein
BACKGROUND: Ferroptosis, a novel manner of cell death depended on iron ion, contributed to goat mammary epithelial cell dysfunction. Interleukin-6 (IL-6) is a major pro-inflammatory factor during many inflammation-related diseases including mastitis, and a quite recently identified ferroptosis induc...
Autores principales: | Zhu, Guangqin, Sui, Shaopu, Shi, Fengyun, Wang, Qinglin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102600/ https://www.ncbi.nlm.nih.gov/pubmed/35549778 http://dx.doi.org/10.1186/s41065-022-00235-y |
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