Mechanism of GAPDH Redox Signaling by H(2)O(2) Activation of a Two−Cysteine Switch

Oxidation of glyceraldehyde−3−phosphate dehydrogenase (GAPDH) by reactive oxygen species such as H(2)O(2) activate pleiotropic signaling pathways is associated with pathophysiological cell fate decisions. Oxidized GAPDH binds chaperone proteins with translocation of the complex to the nucleus and mi...

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Detalles Bibliográficos
Autores principales: Hyslop, Paul A., Chaney, Michael O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102624/
https://www.ncbi.nlm.nih.gov/pubmed/35562998
http://dx.doi.org/10.3390/ijms23094604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102624/
https://www.ncbi.nlm.nih.gov/pubmed/35562998
http://dx.doi.org/10.3390/ijms23094604

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