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Mechanism of GAPDH Redox Signaling by H(2)O(2) Activation of a Two−Cysteine Switch
Oxidation of glyceraldehyde−3−phosphate dehydrogenase (GAPDH) by reactive oxygen species such as H(2)O(2) activate pleiotropic signaling pathways is associated with pathophysiological cell fate decisions. Oxidized GAPDH binds chaperone proteins with translocation of the complex to the nucleus and mi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102624/ https://www.ncbi.nlm.nih.gov/pubmed/35562998 http://dx.doi.org/10.3390/ijms23094604 |