Cargando…

Highly Cytotoxic Osmium(II) Compounds and Their Ruthenium(II) Analogues Targeting Ovarian Carcinoma Cell Lines and Evading Cisplatin Resistance Mechanisms

(1) Background: Ruthenium and osmium complexes attract increasing interest as next generation anticancer drugs. Focusing on structure-activity-relationships of this class of compounds, we report on 17 different ruthenium(II) complexes and four promising osmium(II) analogues with cinnamic acid deriva...

Descripción completa

Detalles Bibliográficos
Autores principales: Hildebrandt, Jana, Häfner, Norman, Kritsch, Daniel, Görls, Helmar, Dürst, Matthias, Runnebaum, Ingo B., Weigand, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102668/
https://www.ncbi.nlm.nih.gov/pubmed/35563367
http://dx.doi.org/10.3390/ijms23094976