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The role of endothelin and RAS/ERK signaling in immunopathogenesis-related fibrosis in patients with systemic sclerosis: an updated review with therapeutic implications

Systemic sclerosis (SSc) is a disease of connective tissue with high rate of morbidity and mortality highlighted by extreme fibrosis affecting various organs such as the dermis, lungs, and heart. Until now, there is no specific cure for the fibrosis occurred in SSc disease. The SSc pathogenesis is y...

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Detalles Bibliográficos
Autores principales: Rokni, Mohsen, Sadeghi Shaker, Mina, Kavosi, Hoda, Shokoofi, Shahrzad, Mahmoudi, Mahdi, Farhadi, Elham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102675/
https://www.ncbi.nlm.nih.gov/pubmed/35562771
http://dx.doi.org/10.1186/s13075-022-02787-w