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Epiregulin increases stemness-associated genes expression and promotes chemoresistance of non-small cell lung cancer via ERK signaling

BACKGROUND: Chemoresistance often causes the failure of treatment and death of patients with advanced non-small-cell lung cancer. However, there is still no resistance genes signature and available enriched signaling derived from a comprehensive RNA-Seq data analysis of lung cancer patients that cou...

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Detalles Bibliográficos
Autores principales: Zhang, Yujia, Qiu, Fengjun, Ye, Tingjie, Lee, Sau Har, Xu, Jiatuo, Jia, Lingyan, Zeng, Rui, Wang, Xiaoling, Hu, Xudong, Yan, Xiaofeng, Li, Hua, Lu, Yanlin, Jiang, Rilei, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102725/
https://www.ncbi.nlm.nih.gov/pubmed/35551652
http://dx.doi.org/10.1186/s13287-022-02859-3