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Identifying potential regulators of JAGGED1 expression in portal mesenchymal cells

OBJECTIVE: Portal mesenchymal cells induce the epithelial differentiation of the bile ducts in the developing liver via one of the Delta-Notch signaling components, JAGGED1. Although this differential induction is crucial for normal liver physiology as its genetic disorder (Alagille syndrome) causes...

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Detalles Bibliográficos
Autores principales: Nishino, Teppei, Yoshihara, Masaharu, Nakayama, Takahiro, Tsuchiya, Takaho, Tahara, Saeko, Ozaki, Haruka, Takahashi, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102744/
https://www.ncbi.nlm.nih.gov/pubmed/35562782
http://dx.doi.org/10.1186/s13104-022-06058-4