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Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney

BACKGROUND: MAPK/ERK signaling is a well-known mediator of extracellular stimuli controlling intracellular responses to growth factors and mechanical cues. The critical requirement of MAPK/ERK signaling for embryonic stem cell maintenance is demonstrated, but specific functions in progenitor regulat...

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Detalles Bibliográficos
Autores principales: Kurtzeborn, Kristen, Kwon, Hyuk Nam, Iaroshenko, Vladislav, Faisal, Imrul, Ambrož, Martin, Jin, Xing, Qureshi, Talha, Kupari, Jussi, Ihermann-Hella, Anneliis, Väänänen, Juho, Tyynismaa, Henna, Boušová, Iva, Park, Sunghyouk, Kuure, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102746/
https://www.ncbi.nlm.nih.gov/pubmed/35550069
http://dx.doi.org/10.1186/s12915-022-01309-z