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Isolation of Echimidine and Its C-7 Isomers from Echium plantagineum L. and Their Hepatotoxic Effect on Rat Hepatocytes

Echimidine is the main pyrrolizidine alkaloid of Echium plantagineum L., a plant domesticated in many countries. Because of echimidine’s toxicity, this alkaloid has become a target of the European Food Safety Authority regulations, especially in regard to honey contamination. In this study, we deter...

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Detalles Bibliográficos
Autores principales: Gleńsk, Michał, Dudek, Marta K., Kinkade, Peter, Santos, Evelyn C. S., Glinski, Vitold B., Ferreira, Daneel, Seweryn, Ewa, Kaźmierski, Sławomir, Calixto, Joao B., Glinski, Jan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102911/
https://www.ncbi.nlm.nih.gov/pubmed/35566223
http://dx.doi.org/10.3390/molecules27092869