Cargando…

NAD(+) Precursors Repair Mitochondrial Function in Diabetes and Prevent Experimental Diabetic Neuropathy

Axon degeneration in diabetic peripheral neuropathy (DPN) is associated with impaired NAD(+) metabolism. We tested whether the administration of NAD(+) precursors, nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR), prevents DPN in models of Type 1 and Type 2 diabetes. NMN was administe...

Descripción completa

Detalles Bibliográficos
Autores principales: Chandrasekaran, Krish, Najimi, Neda, Sagi, Avinash R., Yarlagadda, Sushuma, Salimian, Mohammad, Arvas, Muhammed Ikbal, Hedayat, Ahmad F., Kevas, Yanni, Kadakia, Anand, Russell, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102948/
https://www.ncbi.nlm.nih.gov/pubmed/35563288
http://dx.doi.org/10.3390/ijms23094887