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A Preliminary Investigation of Embedding In Vitro HepaRG Spheroids into Recombinant Human Collagen Type I for the Promotion of Liver Differentiation

Background: In vitro three-dimensional (3D) hepatic spheroid culture has shown great promise in toxicity testing because it better mimics the cell–cell and cell–matrix interactions found in in vivo conditions than that of the traditional two-dimensional (2D) culture. Despite embedding HepaRG spheroi...

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Detalles Bibliográficos
Autores principales: Liao, Fang-Chun, Wang, Yang-Kao, Cheng, Ming-Yang, Tu, Ting-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103061/
https://www.ncbi.nlm.nih.gov/pubmed/35567092
http://dx.doi.org/10.3390/polym14091923