Efficient Fmoc-Protected Amino Ester Hydrolysis Using Green Calcium(II) Iodide as a Protective Agent

In order to modify amino acids, the C-terminus carboxylic acid usually needs to be protected, typically as a methyl ester. However, standard cleavage of methyl esters requires either highly basic or acidic conditions, which are not compatible with Fmoc or acid-labile protecting groups. This highligh...

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Detalles Bibliográficos
Autores principales: Binette, Renaud, Desgagné, Michael, Theaud, Camille, Boudreault, Pierre-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103075/
https://www.ncbi.nlm.nih.gov/pubmed/35566143
http://dx.doi.org/10.3390/molecules27092788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103075/
https://www.ncbi.nlm.nih.gov/pubmed/35566143
http://dx.doi.org/10.3390/molecules27092788

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