Novel Chemicals Derived from Tadalafil Exhibit PRMT5 Inhibition and Promising Activities against Breast Cancer

Breast cancer seriously endangers women’s health worldwide. Protein arginine methyltransferase 5 (PRMT5) is highly expressed in breast cancer and represents a potential druggable target for breast cancer treatment. However, because the currently available clinical PRMT5 inhibitors are relatively lim...

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Detalles Bibliográficos
Autores principales: Yang, Ziyan, Xiao, Tian, Li, Zezhi, Zhang, Jian, Chen, Suning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103191/
https://www.ncbi.nlm.nih.gov/pubmed/35563196
http://dx.doi.org/10.3390/ijms23094806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103191/
https://www.ncbi.nlm.nih.gov/pubmed/35563196
http://dx.doi.org/10.3390/ijms23094806

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