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Novel Chemicals Derived from Tadalafil Exhibit PRMT5 Inhibition and Promising Activities against Breast Cancer

Breast cancer seriously endangers women’s health worldwide. Protein arginine methyltransferase 5 (PRMT5) is highly expressed in breast cancer and represents a potential druggable target for breast cancer treatment. However, because the currently available clinical PRMT5 inhibitors are relatively lim...

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Detalles Bibliográficos
Autores principales:	Yang, Ziyan, Xiao, Tian, Li, Zezhi, Zhang, Jian, Chen, Suning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103191/ https://www.ncbi.nlm.nih.gov/pubmed/35563196 http://dx.doi.org/10.3390/ijms23094806

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