Loss, Gain and Altered Function of GlyR α2 Subunit Mutations in Neurodevelopmental Disorders

Glycine receptors (GlyRs) containing the α2 subunit govern cell fate, neuronal migration and synaptogenesis in the developing cortex and spinal cord. Rare missense variants and microdeletions in the X-linked GlyR α2 subunit gene (GLRA2) have been associated with human autism spectrum disorder (ASD),...

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Detalles Bibliográficos
Autores principales: Chen, Xiumin, Wilson, Katie A., Schaefer, Natascha, De Hayr, Lachlan, Windsor, Mark, Scalais, Emmanuel, van Rijckevorsel, Germaine, Stouffs, Katrien, Villmann, Carmen, O’Mara, Megan L., Lynch, Joseph W., Harvey, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103196/
https://www.ncbi.nlm.nih.gov/pubmed/35571374
http://dx.doi.org/10.3389/fnmol.2022.886729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103196/
https://www.ncbi.nlm.nih.gov/pubmed/35571374
http://dx.doi.org/10.3389/fnmol.2022.886729

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