Conversion of Gastrointestinal Somatostatin-Expressing D Cells Into Insulin-Producing Beta-Like Cells Upon Pax4 Misexpression

Type 1 diabetes results from the autoimmune-mediated loss of insulin-producing beta-cells. Accordingly, important research efforts aim at regenerating these lost beta-cells by converting pre-existing endogenous cells. Following up on previous results demonstrating the conversion of pancreatic somato...

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Detalles Bibliográficos
Autores principales: Garrido-Utrilla, Anna, Ayachi, Chaïma, Friano, Marika Elsa, Atlija, Josipa, Balaji, Shruti, Napolitano, Tiziana, Silvano, Serena, Druelle, Noémie, Collombat, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103212/
https://www.ncbi.nlm.nih.gov/pubmed/35573999
http://dx.doi.org/10.3389/fendo.2022.861922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103212/
https://www.ncbi.nlm.nih.gov/pubmed/35573999
http://dx.doi.org/10.3389/fendo.2022.861922

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