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Conversion of Gastrointestinal Somatostatin-Expressing D Cells Into Insulin-Producing Beta-Like Cells Upon Pax4 Misexpression
Type 1 diabetes results from the autoimmune-mediated loss of insulin-producing beta-cells. Accordingly, important research efforts aim at regenerating these lost beta-cells by converting pre-existing endogenous cells. Following up on previous results demonstrating the conversion of pancreatic somato...
Autores principales: | Garrido-Utrilla, Anna, Ayachi, Chaïma, Friano, Marika Elsa, Atlija, Josipa, Balaji, Shruti, Napolitano, Tiziana, Silvano, Serena, Druelle, Noémie, Collombat, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103212/ https://www.ncbi.nlm.nih.gov/pubmed/35573999 http://dx.doi.org/10.3389/fendo.2022.861922 |
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