Design, Synthesis, and Biological Evaluation of Novel MAO-A Inhibitors Targeting Lung Cancer

Lung cancer is one of the most common causes of cancer-related deaths worldwide. Monoamine Oxidase-A (MAO-A) enzyme mediates the production of reactive oxygen species (ROS) that trigger DNA damage and oxidative injury of cells resulting in tumor initiation and progression. Available MAO-A inhibitors...

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Detalles Bibliográficos
Autores principales: Bardaweel, Sanaa, Aljanabi, Reem, Sabbah, Dima, Sweidan, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103226/
https://www.ncbi.nlm.nih.gov/pubmed/35566238
http://dx.doi.org/10.3390/molecules27092887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103226/
https://www.ncbi.nlm.nih.gov/pubmed/35566238
http://dx.doi.org/10.3390/molecules27092887

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