Reverse Engineering Analysis of the High-Temperature Reversible Oligomerization and Amyloidogenicity of PSD95-PDZ3

PSD95-PDZ3, the third PDZ domain of the post-synaptic density-95 protein (MW 11 kDa), undergoes a peculiar three-state thermal denaturation (N ↔ I(n) ↔ D) and is amyloidogenic. PSD95-PDZ3 in the intermediate state (I) is reversibly oligomerized (RO: Reversible oligomerization). We previously reporte...

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Detalles Bibliográficos
Autores principales: Onchaiya, Sawaros, Saotome, Tomonori, Mizutani, Kenji, Martinez, Jose C., Tame, Jeremy R. H., Kidokoro, Shun-ichi, Kuroda, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103278/
https://www.ncbi.nlm.nih.gov/pubmed/35566161
http://dx.doi.org/10.3390/molecules27092813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103278/
https://www.ncbi.nlm.nih.gov/pubmed/35566161
http://dx.doi.org/10.3390/molecules27092813

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